Adana — A settlement in Cilicia also known as Antiochia ad Sarum - Antiochia ad Cilicia
Adana is a major city in southern Turkey, home to some 6 million people. In Hellenistic times, it was known as Antiochia ad Cilicia or Antiochia ad Sarum ("Antiochia on the Sarus").

The history of Adana is intrinsically linked to the history of Tarsus; they often seem to be the same city, moving as the neighboring Seyhan River changed its position. Their respective names also changed over the course of the centuries. Adana was of relatively minor importance during the Roman's influential period, while nearby Tarsus was the metropolis of the area. During the era of Pompey, the city was used as a prison for the pirates of Cilicia. For several centuries thereafter, it was a waystation on a Roman military road leading to the East.

During Byzantine times, Adana became a Christian bishopric, a suffragan of the metropolitan see of Tarsus, but was raised to the rank of autocephalous archdiocese after 680, the year in which its bishop appeared as a simple bishop at the Third Council of Constantinople, but before its listing in a 10th-century Notitiae Episcopatuum as an archdiocese.

Modern location: Adana, Turkey
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